A client's prenatal testing is positive for cystic fibrosis (CF). Prior to discussing the results with the family, the nurse should consider which information about this test?

Question

Note: Credit will be given only if all correct choices and no incorrect choices are selected.
Standard Text: Select all that apply.
1. The sensitivity of this test varies widely among population groups.
2. This test is a screen and more testing will be required.
3. CF has many manifestation levels.
4. The CF carrier status is rare in the United States.
5. This test only screens for more common selected mutations.

Answer 1

1,2,3,5
Rationale 1: Sensitivity is the test's ability to identify those who are at risk for the condition. The test for CF is more sensitive in some ethnic groups than in others.
Rationale 2: Positive screening tests identify a need for more testing. They do not indicate the child will be affected by the disorder.
Rationale 3: Some children with CF are profoundly affected, while others have very mild manifestations.
Rationale 4: In the U.S. population, carrier rates vary from 1 in 29 to 1 in 90. The condition is not rare.
Rationale 5: The test only screens for a select number of more common mutations.