Explain why mice are appropriate animal models for human behavioral genetics research

What will be an ideal response?


One way to study the genetics of human behavior is to ask whether this behavior can be studied in model systems. If so, then results from experimental organisms can be used to study human behavior. The mouse has been the primary animal used in the study of human psychiatric and other behavioral disorders. Mouse models include strains created by artificial selection for a specific behavior, such as alcohol consumption, and strains created by insertion of a human gene to create a transgenic model of a human behavioral disorder. The genetic similarity between humans and mice (the two species have over 90% of their genes in common) and the application of genomics including genome-wide association studies (GWAS) have increased interest in using the mouse as a model to study illnesses such as schizophrenia and bipolar disorder. These models are being used to investigate the biological mechanisms that underlie specific behaviors, with the expectation that similar mechanisms exist in humans.

Biology & Microbiology

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Investigate green fluorescent protein online, what does it mean to "fluoresce"?

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Biology & Microbiology