Each immunodeficiency syndrome below is paired correctly with its underlying defect except
A) bare lymphocyte syndrome/no CD4 and CD8 complex and therefore no T cells.
B) Wiscott-Aldrich syndrome/defect in production of Wiscott-Aldrich protein necessary for
lymphocytes to change cytoskeletal structure and respond to stimuli.
C) X-linked hyper-IgM/defect in T helper cell CD154 which is required to stimulate B cell
CD40 for immunoglobulin class switching.
D) CD3 complex deficiency/no CD3 complex and therefore no T cells.
E) Bruton's X linked agammaglobulinemia/deficient B cell tyrosine kinase, arrested B cell
maturation, and no circulating mature B cells.
A
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