The nurse is teaching a pharmacology refresher class to a group of medical-surgical nurses. The nurse asks "Alosetron (Lotronex) is approved for which patient population?"
Which response by one of the nurses best indicates understanding of the use of this drug?
a. "It has been approved for use in women with diarrhea-predominant IBS."
b. "It can be given to men with diarrhea and crampy abdominal pain due to IBS."
c. "It would be indicated for pregnant women with iron-associated constipation."
d. "It is approved for use in children whose growth rate is reduced because of IBS."
ANS: A
Alosetron is approved for use in women only with diarrhea-predominant IBS; this statement indicates understanding.
Alosetron is not approved for symptoms of IBS in men, only women; further teaching is needed.
Alosetron is approved only for use in women with IBS associated with diarrhea. It therefore would be contraindicated in pregnant women with iron-associated constipation and children with IBS; further teaching is needed.
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