A teen African American has been prescribed azelaic acid (Azelex) for severe acne. What education about this medication would be most important for the teen to know?
a. Azelaic acid may reduce pigmentation in dark-skinned people.
b. Azelaic acid is more effective than other acne medications.
c. The risk of allergy is higher for azelaic acid than it is for other acne medications.
d. Azelaic acid has been determined to have significant systemic toxicity.
A
The nurse should advise the teen that azelaic acid may reduce pigmentation in dark-skinned people.
Azelaic acid is not more effective than other acne medications. Clinical trials have demonstrated that topical azelaic acid (20%) was equally effective as 5% benzoyl peroxide, 0.05% tretinoin, and 2% erythromycin. For severe acne, topical azelaic acid was much less effective than oral isotretinoin.
The risk of allergy is not greater than with other acne medications.
The drug has no significant systemic toxicity.
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