Individuals who have two defective alleles of the AIRE gene _____

a. exhibit symptoms of autoimmunity at a young age
b. are unable to activate regulatory T cells
c. exhibit decreased predisposition to autoimmune disease
d. are very effective at inducing anergy of circulating autoreactive B and T cells
e. are more likely to be women of African or Asian origin.


a

Health & Biomechanics

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