Growth in length of long bones
What will be an ideal response?
Long bones grow lengthwise by interstitial (longitudinal) growth of epiphyseal plate. Interstitial growth requires presence of epiphyseal cartilage in the epiphyseal plate. The epiphyseal plate consists of 5 zones: resting zones, proliferation zone, hypertonic zone, calcification zone, and ossification zone. Near the end of adolescence, chondroblasts divide less often. Epiphyseal plate thins, then is replaced by bone. Epiphyseal plate closure occurs when epiphysis and diaphysis fuse. Bone lengthening ceases around 18 years old for females, and 21 years old for males.
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