Heat generation via nonshivering thermogenesis is accomplished by cells in which tissue?
a. Brown adipose tissue
b. Liver
c. Skeletal muscle
d. Smooth muscle
e. White adipose tissue
ANS: A
The abundant mitochondria in brown fat cells metabolize fat within multiple lipid droplets in an inefficient manner, involving a protein called uncoupling protein that channels protons into the matrix of a mitochondrion without producing adenosine triphosphate. The energy produced via this pathway appears as heat. See 3-18.
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