Which method of drug excretion excretes most drugs in their original, unmetabolized form?

Question

1. Exhalation
2. Defecation
3. Sweating
4. Urination

Answer 1

Correct Answer: 1

Rationale 1: In contrast to other methods of excretion, the lungs excrete most drugs in their original unmetabolized form, via exhalation.
Rationale 2: Defecation excretes most drugs in a metabolized form.
Rationale 3: Sweating excretes most drugs in a metabolized form.
Rationale 4: Urination excretes most drugs in a metabolized form.

Global Rationale: In contrast to other methods of excretion, the lungs excrete most drugs in their original unmetabolized form, via exhalation. Defecation, sweating, and urination excrete most drugs in a metabolized form.