The "calcium influx factor," or CIF, refers to a factor that:
A. is released by endothelial cells to promote contraction of adjacent smooth muscle
B. facilitates Ca++ refilling of the SR by promoting localized Ca++ influx in the cell
C. is necessary for activation of voltage-gated Ca++ channels in smooth muscle
D. facilitates contraction of smooth muscle by elevating cytosolic Ca++ concentration
E. promotes relaxation of smooth muscle by inducing Ca++ sparks
ANS: B
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