A male patient who has been prescribed isoniazid (INH, Nydrazid) reports that his breasts have enlarged since starting therapy. What is the nurse's best response?
a. "This is common with isoniazid and will disappear after you stop drug therapy."
b. "Is the enlargement the same on both sides or is one breast larger than the other?"
c. "If you are not having difficulty getting an erection, do not worry about this change."
d. "I will report this problem to your prescriber and see if it is possible for you to stop taking this drug."
A
Breast enlargement in men (gynecomastia) is a common side effect of isoniazid. This physical change can be very distressing and embarrassing to men, and they should be reassured that the problem is temporary. Even though it is distressing, breast enlargement is not a reason to stop drug therapy.
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