Describe the action of a Na+-K+ pump

What will be an ideal response?


Three Na+ ions bind to the ICF side of the pump, which allows the pump to then split ATP into ADP and phosphate. The phosphate binds to the pump (i.e., the pump is phosphorylated), which then changes shape and transports the Na+ ions to the ECF. After the Na+ ions leave the pump, two K+ ions attach to the ECF side of the pump, which then causes the phosphate group to detach from the pump. Dephosphorylation causes the pump to change shape and transport the K+ ions into the cell. When the K+ ions detach from the pump, the pump is now ready to repeat the process.

Anatomy & Physiology

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