In the lac operon, what effect does inducer binding have on repressor structure?
What will be an ideal response?
Ans: Inducer binding changes the conformation at the hinge region of the repressor, lowering the affinity of the repressor for DNA.
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Chronic myelogenous leukemia (CML) results from a translocation between human chromosomes 9 and 22. The resulting chromosome 22 is significantly shorter than usual, and it is known as a Philadelphia (Ph') chromosome
The junction at the site of the translocation causes overexpression of a receptor tyrosine kinase. A new drug (Gleevec or imatinib) has been found to inhibit the disease if the patient is treated early. Which of the following would be a reasonably efficient technique for confirming the diagnosis of CML? A) searching for the number of telomeric sequences on chromosome 22 B) looking for a Ph' chromosome in a peripheral blood smear C) enzyme assay for receptor tyrosine kinase activity D) fluorescent labeling to determine the chromosomal location of all chromosome 22 fragments E) identification of the disease phenotype in review of the patient's records
A flower could best be described as which of the following?
A. modified leaves B. modified petals C. modified stems D. primary buds E. incomplete leaves
Which of the following features are common to both moss leaves and true leaves?
A. vascular strands B. chlorophyll a and b C. all the cells are haploid D. except at the midrib only one cell thick E. stomata
The rejection of a transplanted kidney is due to a humoral immune response
Indicate whether the statement is true or false