In the following clinical question, what is the Intervention/influence/exposure (I component): Does taking antidepressants affect the risk of suicide in cognitively impaired adolescents?
A) Adolescence
B) Suicide
C) Antidepressant use
D) Cognitive impairment
C
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In the PIO acronym, P stands for the population or patients (cognitively impaired individuals); I stands for the intervention, influence, or exposure (antidepressants); and O stands for the outcomes (risk of suicide).
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