A 60-year-old patient was admitted to the local hospital presenting with petechiae on his upper torso. Physical examination revealed a thin, pale man

Admission labs came back, and the results revealed the presence of 50% blasts and 25% hypergranular promyelocytes. A bone marrow aspirate was ordered that confirmed the peripheral blood picture. Cytogenetic analysis revealed the following: t (11; 17) (q23; q21). How does this impact the patient's care?

a. The patient has a poorer prognosis because of the chromosomal aberration.
b. The patient has a favorable prognosis because of the chromosomal aberration.
c. The patient will be responsive to all-trans retinoic acid.
d. The patient will be resistant to all-trans retinoic acid, so another treatment will be needed.


Correct Answer: D

Health Professions

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