A prescriber has ordered cefoxitin for a patient who has an infection caused by a gram-negative bacteria
The nurse taking the medication history learns that the patient experienced a maculopapular rash when taking amoxicillin (Amoxil) several years earlier. What will the nurse do?
a. Administer the cefoxitin and observe for any side effects.
b. Give the cefoxitin and have epinephrine and respiratory support available.
c. Request an order for a different, nonpenicillin, noncephalosporin antibiotic.
d. Request an order to administer a skin test before giving the cefoxitin.
ANS: A
Because of structural similarities between penicillins (PCNs) and cephalosporins, a few patients allergic to one drug type will be allergic to the other drug type, although this is rare. For patients with mild PCN allergy, such as rash, cephalosporins can be used with minimal concern, so it is correct to administer the drug and monitor for side effects. It is unnecessary to prepare for anaphylaxis, to give another class of drug, or to administer a skin test.
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