A patient has schizophrenia and is troubled by negative symptoms, muscle stiffness, and motor restlessness

His Advanced Practice Nurse (APN) is considering changing the patient's antipsychotic medication, haloperidol (Haldol, a typical or first generation antipsychotic drug). For planning purposes, which medication can the nurse assume that the APN will probably choose? a. Chlorpromazine (Thorazine)
b. Clozapine (Clozaril)
c. Olanzapine (Zyprexa)
d. Fluoxetine (Prozac)


C
Olanzapine is an atypical antipsychotic that produces few extrapyramidal side effects (EPS) and is effective in treating both positive and negative symptoms of schizophrenia. Chlorpromazine often produces EPS and is not effective in treating negative symptoms. Clozapine produces fewer EPS but would not be the drug of choice because of the danger of agranulocytosis. Fluoxetine is a selective serotonin reuptake inhibitor antidepressant.

Nursing

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