A young woman who is planning to start a family states that she had a retinoblastoma as a child. The woman and her husband are concerned about the chances of their son or daughter developing a retinoblastoma
It is important that the nurse inform the couple that:
A) It is an autosomal recessive inheritance in which each parent carries the gene mutation.
B) It is an X-linked inheritance and all males inherit an X chromosome from their mothers.
C) It is an autosomal dominant inheritance which has incomplete penetrance and can skip a generation.
D) It is a pattern that is more horizontal than vertical; relatives of a single generation tend to have the condition.
Ans: C
Feedback: Retinoblastoma is an autosomal dominant inheritance which has incomplete penetrance and the gene appears to skip a generation, thus leading to errors in interpreting family history and in genetic counseling. Autosomal recessive conditions have a pattern that is more horizontal than vertical; relatives of a single generation tend to have the condition. Genetic conditions inherited in an autosomal recessive pattern are frequently seen among particular ethnic groups and usually occur more often in children of parents who are related by blood, such as first cousins. X-linked conditions may be inherited in recessive or dominant patterns. In both, the gene mutation is located on the X chromosome.
You might also like to view...
The Mental Health Status Exam takes place in what step of the nursing process?
A. Evaluation B. Nursing diagnosis C. Intervention D. Assessment
Which of these statements about a client with one S gene (HbSA) who has sickle-cell trait is TRUE?
a. The client is asymptomatic and cannot pass the disease on to offspring. b. The client is asymptomatic but is a carrier of the disease and may pass it on to offspring. c. The client is symptomatic but cannot pass the disease on to offspring. d. The client is symptomatic but is a carrier of the disease and may pass it on to offspring.
When assessing a 2-year-old child with suspected autistic disorder, the nurse should be particularly
alert for a. failure to develop interpersonal skills. b. hyperactivity and attention deficits. c. high levels of anxiety when separated from the mother. d. a history of disobedience and destructive acts.
An older adult client comes in to the office with severe sunburn. When reviewing the client's medication list, which is the likely cause of the client's sunburn?
1. Phenytoin (Dilantin) 2. Cyclobenzaprine (Flexeril) 3. Naproxen (Aleve) 4. Alprazolam (Xanax)