A patient with chronic gout is admitted to the hospital for treatment for an infection. The patient is receiving allopurinol and ampicillin

The nurse is preparing to administer medications and notes that the patient has a temperature of 101°F and a rash. What will the nurse do? a. Withhold the allopurinol and notify the prescriber of the drug reaction.
b. Withhold the ampicillin and contact the provider to request a different antibiotic.
c. Request an order for an antihistamine to minimize the drug side effects.
d. Suggest giving a lower dose of the allopu-rinol while giving ampicillin.


A
Allopurinol can cause a hypersensitivity syndrome, which is characterized by a rash and fever. If these occur, the drug should be discontinued immediately. The combination of ampicillin and allopurinol increases the risk of this reaction; if it occurs, the allopurinol, not the ampicillin, should be discontinued. Antihistamines are not indicated. Lowering the dose of allopurinol is not indicated.

Nursing

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