The mechanism of action of selective estrogen receptor modulators (SERMs), such as raloxifene (Evista), is to
1. increase calcium levels in the bone.
2. slow bone resorption.
3. inhibit synthesis of microtubules.
4. increase bone mass and density.
Correct Answer: 4
Rationale 1: Calcium supplements increase calcium levels.
Rationale 2: Bisphosphonates slow bone resorption.
Rationale 3: Selective estrogen receptor modulators do not inhibit synthesis of microtubules.
Rationale 4: Selective estrogen receptor modulators increase bone mass and density through the estrogen receptor.
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