An adult patient has recently begun cancer treatment with methotrexate (MTX). The nurse is aware of the importance of monitoring the patient closely for adverse effects of treatment
When reviewing this patient's laboratory work, the nurse should consequently prioritize assessment of which of the following? A) Sodium and potassium
B) BUN and creatinine
C) Calcium and magnesium
D) Arterial blood gases
B
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The antimetabolites may also be nephrotoxic. MTX use in patients with impaired renal function may lead to accumulation of toxic amounts or additional renal damage. Evaluation of the patient's renal status should take place before and during MTX therapy. This adverse effect of MTX treatment supersedes the importance of electrolytes and ABGs, though these would also be considered.
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Fill in the blank(s) with correct word