Which immune responses can result in harm to the body? (Select all that apply.)
a. Activation of the complement system
b. Autoimmune response
c. IgE binding to mast cells and basophils
d. Opsonization
e. Recognition of MHC molecules as nonself
B, C, E
The autoimmune response causes the immune system to attack the body's own cells. The hyper-sensitivity response, mediated by IgE, causes the release of harmful chemical mediators. Recog-nition of MHC molecules as nonself in a transplanted organ can cause organ rejection. Activation of the complement system causes a cascade of reactions that assist in the immune response. Opsonization is a process that assists with phagocytosis.
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