The client has a medical diagnosis of schizophrenia, and receives aripiprazole (Abilify). What is the primary expected client outcome related to dopamine reduction?

1. Client will have reduced psychotic behavior.
2. Client will have improved sleep patterns.
3. Client will decrease anxiety.
4. Client will improve social relationships.


1

Rationale 1: A main theory of schizophrenia is that the brain produces too much dopamine. Antipsychotic drugs act by attaching to dopamine receptors in the postsynaptic neurons of the brain. This prevents dopamine from attaching to and stimulating the receptors. Thus, psychotic behavior is reduced when the dopamine receptors are blocked by antipsychotic drugs.
Rationale 2:An improvement in sleep patterns is not directly related to a reduction in dopamine. However, sleep patterns might improve when the psychotic behavior is reduced.
Rationale 3:The medication will not decrease the anxiety. However, anxiety might be decreased when the psychotic behavior is reduced.
Rationale 4: Client will not improve social relationships because dopamine reduction by itself does not improve social relationships. A client needs therapy to improve social relationships.

Global Rationale: A main theory of schizophrenia is that the brain produces too much dopamine. Antipsychotic drugs act by attaching to dopamine receptors in the postsynaptic neurons of the brain. This prevents dopamine from attaching to and stimulating the receptors. Thus, psychotic behavior is reduced when the dopamine receptors are blocked by antipsychotic drugs, such as aripiprazole (Abilify).

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