Which of the following correctly represents the probability that a detrimental autosomal recessive
allele will actually be expressed in a population if the occurrence of the allele is such that 1 in 50
individuals are heterozygous?
a. 1/50 ? 1/50 = 1/2500, with 1/4 of their children homozygous recessive = 1/2500 ? 1/4 =
1/10,000.
b. 1/50 ? 1/4 that are homozygous recessive = 1/200.
c. 1/50 ? 2 children (on average) ? 1/4 that are homozygous recessive = 1/100.
d. 1/50 ? 2 parents ? 4 children ? 1/4 that are homozygous recessive = 1/25.
e. Cannot be determined from the information given.
A
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