What is one difference between using restriction endonucleases and mechanical shearing of DNA?

A) Restriction endonucleases cut DNA at known specific sites while shearing occurs at random sites.
B) Restriction endonucleases cut DNA at random sites while shearing occurs at known specific sites.
C) DNA cut with restriction enzymes can be used for cloning and DNA broken by shearing cannot.
D) Restriction enzymes produce larger fragments on average than shearing.


A) Restriction endonucleases cut DNA at known specific sites while shearing occurs at random sites.

Biology & Microbiology

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