An adult client who prescribed the anticholinergic oxybutynin (Ditropan) for urinary incontinence is admitted to the unit with acute muscle spasms after twisting her back in a fall
Which medication used for muscle spasm relaxation would cause the nurse the most concern?
1. Ibuprofen 600 mg
2. Cyclobenzaprine (Flexeril)
3. Tizanidine (Zanaflex)
4. Chlorzoxazone (Parafon Forte)
Correct Answer: 2
Rationale 1: There is no contraindication for use of ibuprofen with anticholinergics.
Rationale 2: Cyclobenzaprine will enhance anticholinergic side effects and is contraindicated with anticholinergics.
Rationale 3: There is no contraindication for use of tizanidine with anticholinergics.
Rationale 4: There is no contraindication for use of chlorzoxazone with anticholinergics.
Global Rationale: Cyclobenzaprine will enhance anticholinergic side effects and is contraindicated with anticholinergics. There is no contraindication for use of ibuprofen, tizanidine, orchlorzoxazone with anticholinergics.
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