Tamoxifen is commonly used in the treatment of breast cancer because it:
a. Decreases the need for surgery
b. Is effective at controlling side effects of chemotherapy
c. Blocks estrogen in tumors that are stimulated by estrogen
d. Has no side effects and improves response to other drugs
ANS: C
Tamoxifen is used after surgery to suppress growth of tumors that are estrogen receptor positive. Tamoxifen blocks estrogen, thereby removing a contributing factor to tumor growth.
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