A primary care NP sees a 46-year-old male patient and orders a fasting lipoprotein profile that reveals LDL of 190 mg/dL, HDL of 40 mg/dL, and triglycerides of 200 mg/dL
The patient has no previous history of coronary heart disease, but the patient's father developed coronary heart disease at age 55 years. The NP should prescribe: a. atorvastatin (Lipitor).
b. gemfibrozil (Lopid).
c. cholestyramine (Questran).
d. lovastatin/niacin (Advicor).
A
HMG-CoA reductase inhibitors are used to treat hyperlipidemia when the LDL is the primary lipid elevation. This patient has risk factors of being a man older than 45 years, with a positive family history of coronary heart disease before age 55 in a male first-degree relative. Gemfibrozil is used for patients with elevated triglycerides and low HDL. Bile acid sequestrants are used as adjunctive and not first-line therapy for reducing LDL. A combination product is not indicated for first-line therapy.
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