Which statements are true regarding chlorpromazine (Thorazine)?(Select all that apply.)

1. Many clients overdose on this medication.
2. Delay in achieving an orgasm.
3. Anticholinergic effects such as dry mouth, postural hypotension, and urinary retention are common.
4. Chlorpromazine (Thorazine) has a wide safety margin between a therapeutic and a lethal dose.
5. This drug will cause psychological dependence.


2, 3, 4

Rationale 1:Many clients overdose on this medication is incorrect because there is a wide safety margin, and death due to overdose is highly unlikely.
Rationale 2:There is a delay in achieving orgasm for both men and women.
Rationale 3: Anticholinergic effects such as dry mouth, postural hypotension, and urinary retention are common.
Rationale 4: Antipsychotic drugs have a wide safety margin between a therapeutic and a lethal dose; deaths due to overdoses of antipsychotic drugs are uncommon.
Rationale 5:Antipsychotic drugs do not cause psychological dependence.

Global Rationale: Chlorpromazine (Thorazine) is a phenothiazine and does not cause psychological dependence. Anticholinergic effects such as dry mouth, postural hypotension, and urinary retention are common.Ejaculation disorders occur in a high percentage of patients; delay in achieving orgasm in both men and women is a common cause for noncompliance. They also have a wide safety margin between a therapeutic and a lethal dose; deaths due to overdoses of antipsychotic drugs are uncommon.

Nursing

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