Explain how B cells undergo the process of negative selection and indicate at which stage of development and at which location these events occur
What will be an ideal response?
Immature B cells that express receptors specific for common multivalent self antigens undergo apoptosis unless receptor editing can produce a receptor that does not have specificity for self antigen. This process of clonal deletion begins in the bone marrow, and apoptotic cells are phagocytosed by macrophages. Immature B cells bearing receptors for monovalent self antigen are instead rendered anergic. These anergic B cells are produced in the bone marrow and when exported to the periphery survive for only 1–5 days. Immature B cells reactive to self antigen in the periphery cannot carry out receptor editing. They either undergo apoptosis or become anergic.
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A) Flow sheet (graphic sheet) B) Admission sheet C) Patient information sheet D) Vital statistics sheet
Which of the following conditions could cause jaundice?
a. ulcerative colitis b. gastroesophageal reflux c. dysentery d. cirrhosis
____________________ disease is a chronic autoimmune disorder that is most often found in the ileum and in the colon
Fill in the blank(s) with correct word
Which of the following states Franklin Henry's views on physical education?
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