Match the terms with their proper definitions
A) shows the number of animals who responded or do not respond to a drug and at what doses.
B) the dose at which 50 percent of the animals tested had toxic levels of the drug
C) the time required for drug levels in the serum to decrease from 100 percent to 50 percent.
D) relative margin of safety between the dose that produces a therapeutic effect and the dose that produces a lethal effect in animals
E) the dose at which 50 percent of the animals tested show a therapeutic response to the drug
1) frequency distribution curve
2) half-life
3) median effective dose (ED50)
4) median toxicity dose (TD50)
5) therapeutic index (TI)
Answers: 1) A 2) C 3) E 4) B 5) D
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