A patient is newly diagnosed with multiple sclerosis (MS). What physiological change is causing the patient's symptoms?
a. Depletion of dopamine in the central nervous system (CNS)
b. Demyelination of nerve fibers in the CNS
c. The development of neurofibril webs in the CNS
d. Reduced amounts of acetylcholine at the neuromuscular junction
ANS: B
The pathophysiology of MS includes demyelination of nerve fibers. Depletion of dopamine is related to Parkinson disease. The development of neurofibrils is related to Alzheimer disease. Myasthenia gravis is due to decreased amounts of acetylcholine at the junction.
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