Which statement best describes the concept of multifactorial inheritance?
a. A mutation in a single gene results in the expression of problems in a variety of tis-sues and organs.
b. Susceptibility to a problem is inherited as a single gene trait, but development of the problem is enhanced by environmental conditions.
c. A mutated gene is inherited, but the re-sults of expression of that gene are not evident until middle or late adulthood.
d. Several genes are responsible for the me-chanism of hearing, and a mutation in any one of them results in hearing impairment.
B
Multifactorial inheritance indicates an interaction between a genetic predisposition and the envi-ronment. Although the predisposition to developing a health problem may be inherited, whether the problem is ever expressed is determined by environmental influences, including lifestyle. Some common adult health problems that are multifactorial include hypertension, obesity, di-abetes mellitus, and some types of cancer. Multifactorial inheritance does not refer to mutations in one gene that result in problems in many tissues and organs. Although it is true that a gene mutation may not become evident until later in life, this is not the definition of multifactorial in-heritance. It does not refer to mutations in several genes or to conditions in which several genes are involved.
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