An African American patient says, "I have heard that people of my race have a higher incidence of Alzheimer's disease. I am afraid I will get it, too."
The nurse recognizes which factor from this patient's history as indicating the greatest risk? 1. The patient has two uncles who developed Alzheimer's disease after age 70.
2. The patient's sister, who has Down syndrome, developed Alzheimer's disease at age 45.
3. The patient's mother developed Alzheimer's disease at age 54.
4. The patient's father developed Parkinson's disease at age 65.
3
Rationale 1: Aging is a risk factor for development of AD, and the uncles are not first-degree relatives. Another factor is a greater risk.
Rationale 2: A high percentage of people with Down syndrome develop AD around age 40. If this patient does not have Down syndrome, his risk is not elevated for this reason.
Rationale 3: Early-onset AD may be genetically linked. African Americans who have first-degree relatives with AD have a higher risk of dementia.
Rationale 4: There is currently no information to indicate that a person whose parent develops late-onset Parkinson's disease has a higher risk for developing AD.
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