Pancreatic beta cells secrete insulin, which inhibits secretion of glucagon from neighboring alpha cells. This action is an example of which of the following signaling types?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS: A
Paracrine signaling involves the release of local chemical mediators that are quickly taken up, de-stroyed, or immobilized, as in the case of insulin and the inhibition of the secretion of glucagon. None of the other options involve signaling that is associated with a local chemical mediator like insulin.
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