The nurse is caring for a 45-year-old female patient who is in chronic renal failure. What cholinergic drug is contraindicated for this patient?
A) Neostigmine
B) Pyridostigmine
C) Edrophonium
D) Galantamine
D
Feedback:
Drugs used to treat Alzheimer's disease are metabolized in the liver and excreted in the urine, so caution should be used in the presence of hepatic or renal dysfunction, which could interfere with the metabolism and excretion of the drugs. Dosage adjustments may be needed for neostigmine, edrophonium, and pyridostigmine if the patient has renal disease but they are not contraindicated.
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