Indicate which of the following statements is true (T) or false (F)
a. __ Immature T cells failing to successfully recombine a ?-chain locus die by apoptosis.
b. __ Apoptotic T cells are ingested by medullary epithelial cells.
c. __ Allelic exclusion of the T-cell receptor ? and ? chains is effective; therefore, all T cells express only one T-cell receptor on the cell surface.
d. __ T-cell receptor rearrangements have many features in common with immunoglobulin rearrangement, including the use of the RAG-1 and RAG-2 genes.
e. __ The expression of the pre-T-cell receptor is required in order to halt ?-, ?-, and ?-chain rearrangements.
a—F; b—F; c—F; d—T; e—T
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