A patient has been started on ticlopidine (Ticlid) after a myocardial infarction and stent placement. How should the nurse explain the action of this medication to the patient?
1. "Ticlid will dissolve any clots that might form in your stent."
2. "Ticlid will make the platelets in your blood less sticky."
3. "Ticlid will change the way your platelets work their entire lives."
4. "Ticlid decreases your blood's ability to clot."
5. "Ticlid works just like the heparin you have been on in the hospital."
Correct Answer: 2,3,4
Rationale 1: Ticlid does not act to dissolve clots.
Rationale 2: Ticlid is an adenosine diphosphate (ADP) receptor blocker that acts to make platelets unable to aggregate, thus rendering them less "sticky."
Rationale 3: Ticlid causes irreversible changes in platelet plasma membranes.
Rationale 4: Ticlid does decrease the blood's ability to clot.
Rationale 5: The mechanisms of action of Ticlid and heparin are not alike.
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