An adolescent is receiving methotrexate chemotherapy after undergoing limb-salvage surgery for osteogenic sarcoma. The nurse knows the teen understands the purpose of leucovorin therapy after the methotrexate if the teen says

"I'm glad I only need one dose of the
leucovorin."
2. "I don't have any pain so I won't need
to take the leucovorin this time."
3. "I know I will be taking the
leucovorin every six hours for about
the next three days."
4. "I don't have any nausea so I won't
need the leucovorin."


Answer: 3
Rationale: Leucovorin (citrovorum factor) is a form of folic acid that helps to
protect normal cells from the destructive action of methotrexate. It is started
within 24 hours of methotrexate administration and is given along with
hydration therapy. Usual administration is every six hours times 72 hours or until
serum methotrexate is at the desired level.

Nursing

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