A nurse is providing care to a client diagnosed with benign prostatic hypertrophy. The nurse understands that which of the following drugs inhibit the conversion of testosterone into 5-alpha-dihydrotestosterone (DHT),
resulting in a decrease in prostate gland size? Select all that apply.
A) Terazosin (Hytrin)
B) Finasteride (Proscar)
C) Methyltestosterone (Testred)
D) Dutasteride (Avodart)
E) Doxazosin (Cardura)
Ans: B, D
Feedback:
Finasteride (Proscar) and dutasteride (Avodart) inhibit the conversion of testosterone into 5-alpha-dihydrotestosterone (DHT), which results in a decrease in prostate gland size, making them useful in the treatment of benign prostatic hypertrophy.
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