Explain the mechanism by which oxygen perfusion is increased in hypoxic muscle tissue
What will be an ideal response?
Answer: When endothelial cells experience hypoxia, levels of hypoxia-inducible factor increase and trigger the release of the hormone vascular endothelial growth factor into the walls of the blood vessels, binding specific receptors. The response is cell proliferation and the ultimate growth of blood vessels into hypoxic tissues, thereby increasing the rates of perfusion.
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Which embryonic layer gives rise to the lamina propria and muscularis externa?
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