A 51-year-old female has been found to have a metastatic lesion in her lung, and her oncologist is unsure of the site of the primary tumor. Which of the following procedures is most likely to aid in this determination?
A)
Immunohistochemistry
B)
Tumor markers
C)
Microarray technology
D)
Tissue biopsy
Ans:
A
Feedback:
Immunohistochemistry can be used to determine the site of origin of metastatic tumors. In cases in which the origin of the metastasis is obscure, immunochemical detection of tissue-specific or organ-specific antigens can often help to identify the tumor source. Tumor markers, microarray technology, and biopsy are less likely to aid in identifying the primary source.
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