A 4-year-old boy presents with a chronic cough and swollen lymph nodes. His records show that he has been given antibiotics several times in the past year with limited success,

most recently for a liver abscess, and that he also has a recurring fungal skin condition. Which of the following is his most likely diagnosis?
A)
Selective IgA deficiency
B)
A deficiency in IgG2 subclass antibodies
C)
Chronic granulomatous disease
D)
Ataxia-telangiectasia


Ans:
C

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Chronic granulomatous disease, because it affects phagocytic function, increases susceptibility to soft tissue infections, particularly of the skin, lungs, lymph nodes, and liver. Selective IgA deficiency and deficient IgG2 subclass antibodies can predispose people to infection, but those infections respond readily to antibiotic treatment. Ataxia-telangiectasia can cause skin and liver problems, but its primary manifestations are ataxia and telangiectasia.

Nursing

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