A nurse is reviewing drug safety with a student nurse. The nurse explains that the median lethal dose of drugs is often determined in laboratory preclinical trials because of which factors?
A. It would be unethical to determine these values in human subjects.
B. The safety of the medication must be determined prior to clinical trials.
C. It is difficult to obtain sufficient participants for clinical trials.
D. Clinical trials determine only the effective dose of a drug.
E. It is too costly to conduct the studies during clinical trials.
Answer:
A. It would be unethical to determine these values in human subjects.
B. The safety of the medication must be determined prior to clinical trials.
You might also like to view...
The nurse is caring for an 88-year-old patient who is recovering from an ileac-femoral bypass graft. The patient is day 2 postoperative and has been mentally intact, as per baseline
When the nurse assesses the patient, it is clear that he is confused and has been experiencing disturbed sleep patterns and impaired psychomotor skills. What should the nurse suspect is the problem with the patient? A) Postoperative delirium B) Postoperative dementia C) Senile dementia D) Senile confusion
Which statement is the most appropriate advice to give parents of a 16-year-old who is rebellious?
a. "You need to be stricter so that your teen stops trying to test the limits." b. "You need to collaborate with your daughter and set limits that are perceived as being reasonable." c. "Increasing your teen's involvement with her peers will improve her self-esteem." d. "Allow your teenager to choose the type of discipline that is used in your home."
The physician has prescribed sertraline (Zoloft) for the patient who is anxious and depressed. The patient calls the nurse to report that he has experienced delayed ejaculation since being on this medication. What is the best response by the nurse?
1. "I will let your doctor know, and he will most likely change your medication." 2. "This does happen, but treating your depression is a bigger priority." 3. "I am concerned that you will become suicidal if you stop the medication." 4. "Keep taking the medicine, as this usually goes away after a few months."
How does the nurse perform the bimanual technique of palpation to assess organs?
a. Using the palmar surface of the dominant hand to press inward to a depth of about 1 cm b. Holding a light source in one hand while stroking the skin lightly with the dominant hand c. Using the ulnar surfaces of both hands to press inward 4 to 5 cm d. Using both hands, one anterior and one posterior, to entrap an organ between the fingertips