What would be the consequences to a phage that lysogenized in a recA? bacterial cell? Explain why this would occur
What will be an ideal response?
Induction (the termination of lysogeny and the reinitiation of the lytic cycle) would not occur, so the prophage would be unable to excise from the bacterial chromosome and re-enter the lytic cycle. Normally the RecA protein cleaves the repressor protein, disrupting the dimer and resulting in the loss of binding of the repressor to OR1, OR2, and OR3. Positive regulation of cI and negative regulation of cro end, resulting in a transition from lysogeny to the lytic cycle. In the absence of RecA, the repressor is not cleaved, positive regulation of cI and negative regulation of cro continue, so lysogeny is maintained.
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