You make a knockout of a gene involved in neurological development, and find that the mice have malformed semicircular canals. Instead of being orthogonal (at right angles) to each other, they are parallel. What aberrant behavior might you see in these mice?
A. Low muscle tone
B. Not startling to sudden noise
C. Falling over
D. Unable to respond to a call to locate another mouse
E. Overeating
Answer: C
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In this representation of transcription, strand #
2 represents
a. the coding DNA strand. b. the transcript. c. the template for the coding DNA strand. d. the coded RNA strand. e. both the transcript and the coded RNA strand.
Which is NOT ordinarily capable of being reduced at
any time? a. NAD+ b. FAD c. oxygen, O2 d. water e. all of these
The normal human karyotype contains __________ chromosomes
a. 22 b. 23 c. 44 d. 46 e. 54
In the 1940s, some physicians prescribed low doses of a drug called dinitrophenol (DNP) to help patients lose weight. This unsafe drug was quickly abandoned after a few patients died
DNP affects cells by uncoupling the chemiosmotic machinery and making the inner mitochondrial membrane "leaky" to hydrogen ions. Explain how DNP caused weight loss and, ultimately, death in these dieters.