A client is ordered a nitroglycerine transdermal patch for treatment of CAD and asks the nurse why the patch is removed at bedtime. Which is the best response by the nurse?

A) "Nitroglycerine causes headaches, but removing the patch decreases the incidence."
B) "You do not need the effects of nitroglycerine while you sleep."
C) "Removing the patch at night prevents drug tolerance while keeping the benefits."
D) "Contact dermatitis and skin irritations are common when the patch remains on all day."


C
Feedback:
Tolerance to antiangina effects of nitrates can occur when taking these drugs for long periods of time. Therefore, to prevent tolerance and maintain benefits, it is a common regime to remove transdermal patches at night. Common adverse effects of nitroglycerine are headaches and contact dermatitis but not the reason for removing the patch at night. It is true that while you rest, there is less demand on the heart but not the primary reason for removing the patch.

Nursing

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