In the 1950s, researchers began searching for safer medications to treat rheumatoid arthritis (RA). Prior to this time, RA was treated with aspirin and corticosteroids

Which drug was identified by the researchers to be safer in the treatment of inflammation and pain for RA clients?
1. Gold compounds
2. Acetaminophen (Tylenol)
3. Celecoxib (Celebrex)
4. Ibuprofen (Motrin, Advil, others)


Correct Answer: 4
Rationale 1: Gold compounds can be toxic.
Rationale 2: Acetaminophen is administered for pain relief, but it has no anti-inflammatory properties.
Rationale 3: Celecoxib (Celebrex) was introduced as a treatment for arthritis in the 1990s.
Rationale 4: Ibuprofen was introduced in the United States in 1974, and it became one of the first prescription-only drugs that were changed to OTC status in 1984.
Global Rationale: An exhaustive search of over 600 potential compounds over a 15-year period resulted in the discovery of ibuprofen, one of the safest and most widely prescribed NSAIDs in the world. The drug was introduced in the United States in 1974, and it became one of the first prescription-only drugs to be changed to OTC status in 1984. Gold compounds can be toxic. Acetaminophen is administered for pain relief, but it has no anti-inflammatory properties. Celecoxib (Celebrex) was introduced as a treatment for arthritis in the 1990s.

Nursing

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