A mother rushes her 4-year-old child to the emergency department after she found an empty Tylenol (acetaminophen) bottle beside her child
The nurse is trying to explain why it is so important to give the child Ipecac to induce vomiting in order to prevent:
A) Renal failure
B) Seizures
C) Liver failure
D) Hemorrhage
Ans: C
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Acetaminophen, a commonly used over-the-counter analgesic drug, is detoxified in the liver, where small amounts of the drug are converted to a highly toxic metabolite. This metabolite is detoxified by a metabolic pathway that uses a substance normally present in the liver. When large amounts of the drug are ingested, this pathway becomes overwhelmed and toxic metabolites accumulate, causing massive liver necrosis.
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