In a typical epiphyseal (growth) plate, which zone of cartilage is closest to the marrow cavity?
a. Zone of reserve cartilage
b. Zone of proliferating cartilage
c. Zone of hypertrophic cartilage
d. Zone of calcifying cartilage
e. Zone of ossification
ANS: E
Complete ossification can only take place when cartilage matrix is exposed to osteoblasts that migrate from the capillaries of the marrow cavity. Other regions of cartilage are avascular and thus do not allow the entry of osteoblasts.
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